Pyrantel pamoate 250 mg (Nemocid 250 Tablet)

Nemocid 250 mg Tablet, containing Pyrantel Pamoate as its active ingredient, is an anthelmintic medication used to treat intestinal worm infections such as pinworm (Enterobiasis), roundworm (Ascariasis), hookworm (Ancylostomiasis), and other parasitic worm infections. Manufactured by Ipca Laboratories Ltd., it works by paralyzing the worms, allowing them to be expelled from the body through natural bowel movements. Available as a tablet or oral suspension, Nemocid is a reliable choice for both adults and children above 2 years, offering effective deworming with a single-dose regimen in most cases.

Benefits

• Broad-Spectrum Deworming: Effectively treats multiple intestinal worm infections, including pinworms, roundworms, hookworms, and Strongyloides, providing comprehensive parasite control.

• Rapid Action: Symptoms often improve quickly, typically within a few days, as the medication paralyzes and eliminates worms efficiently.

• Ease of Administration: Available in tablet form for easy swallowing or as a suspension for children, with the option to take with or without food, enhancing compliance.

• Family-Wide Treatment: Suitable for treating all household members in close contact to prevent the spread of highly contagious infections like pinworms.

• Non-Habit Forming: No risk of dependency, making it safe for periodic use as prescribed.

Uses

• Primary Indication: Treatment of intestinal worm infections, including pinworms, roundworms, hookworms, trichinosis, and necatoriasis.

• Additional Uses:

  • Mass treatment in endemic areas to control susceptible worm infections.

  • Potential use in combination therapies for mixed parasitic infections, under medical supervision.

• Administration: Typically taken as a single 250 mg dose for adults and children above 2 years, based on body weight (approximately 11 mg/kg). A repeat dose may be required after 2 weeks for certain infections like pinworms to prevent reinfection. Can be taken with food, juice, or milk, preferably at a fixed time.

Side Effects

• Common Side Effects (usually mild and resolve without intervention):

  • Headache

  • Dizziness

  • Nausea

  • Vomiting

  • Abdominal pain or cramps

  • Diarrhea

  • Loss of appetite

  • Trouble sleeping

  • Hair loss (rare)

  • Vertigo

• Serious Side Effects (rare, seek immediate medical attention):

  • Allergic reactions (skin rash, itching/swelling, severe dizziness, breathing difficulty)

  • Persistent or severe abdominal pain

  • Abnormal liver function tests

  • Fever

• Note: Most side effects are temporary and subside as the body adjusts. Consult a doctor if symptoms persist or worsen.

Safety Nemocid 250 mg Tablet

• Contraindications:

  • Hypersensitivity to Pyrantel Pamoate or any tablet components.

  • Severe malnutrition or anemia (use with caution and supportive therapy).

  • Liver disease (use only under medical supervision due to potential worsening).

• Precautions:

  • Pregnancy: Not recommended in the first trimester due to limited safety data; use only if benefits outweigh risks, as advised by a doctor.

  • Breastfeeding: Limited data suggests minimal risk but consult a doctor before use.

  • Children: Not recommended for children under 2 years due to insufficient safety data.

  • Liver Impairment: Use cautiously; regular monitoring of liver function tests is advised.

  • Driving: May cause dizziness or drowsiness; avoid driving or operating heavy machinery until effects are known.

  • Hygiene: Maintain good personal hygiene (e.g., handwashing, washing linens, avoiding barefoot walking in endemic areas) to prevent reinfection.

• Drug Interactions:

  • Piperazine: May reduce Pyrantel Pamoate’s efficacy; avoid concurrent use.

  • Aminophylline/Theophylline: Pyrantel may increase blood levels or reduce efficacy; monitor closely.

  • Sodium iodide (I-123/I-131) or laxatives: Potential interactions; avoid unless prescribed.

• Storage: Store in a cool, dry place below 30°C, away from moisture and direct sunlight. Keep out of reach of children.

• Overdose: Symptoms include severe nausea, vomiting, and abdominal cramps. Seek immediate medical attention.

• Disposal: Do not flush; use a medicine take-back program or consult a pharmacist for proper disposal.