Susten 300 SR (Progesterone)

What is Susten 300 SR?

Susten 300 SR Tablet is a prescription medication containing natural micronized progesterone (300 mg), a key female hormone, in a sustained-release formulation. Manufactured by Sun Pharmaceutical Industries Ltd., it provides a gradual release of progesterone to maintain consistent hormone levels. It is used to treat progesterone deficiency, supporting pregnancy, regulating menstrual cycles, and managing hormonal imbalances by mimicking the action of progesterone produced by the ovaries, which prepares the uterus for pregnancy and prevents premature contractions.

Benefits

• Consistent Hormone Levels: Sustained-release formulation ensures steady progesterone delivery, improving treatment efficacy and convenience with once-daily dosing.

• Supports Pregnancy: Thickens the uterine lining to aid embryo implantation and reduces miscarriage risk in women with low progesterone levels.

• Regulates Menstrual Cycles: Restores regular periods in women with secondary amenorrhea due to progesterone deficiency.

• Manages Menopausal Symptoms: When used in hormone replacement therapy (HRT) with estrogen, it alleviates symptoms like hot flashes and prevents endometrial hyperplasia.

Susten 300 SR (Progesterone) Uses

• Female Infertility: Supports luteal phase in assisted reproductive technologies (e.g., IVF) to enhance embryo implantation and pregnancy success.

• Threatened Miscarriage: Maintains early pregnancy in women with a history of recurrent miscarriages due to luteal phase defects.

• Secondary Amenorrhea: Induces menstruation in non-menopausal women with absent periods caused by low progesterone.

• Hormone Replacement Therapy: Combined with estrogen to prevent endometrial hyperplasia in menopausal women and manage menopausal symptoms.

• Menstrual Disorders: Treats irregular or heavy uterine bleeding due to hormonal imbalances, including conditions like endometriosis or premenstrual syndrome (PMS).

Side Effects

• Common: Headache, dizziness, drowsiness, nausea, bloating, abdominal pain, breast tenderness, hot flashes, vaginal discharge, joint pain, mood swings, or constipation. These are typically mild and resolve over time.

• Serious (Rare): Blood clots (e.g., deep vein thrombosis, pulmonary embolism), severe allergic reactions (rash, swelling, breathing difficulty), jaundice, abnormal vaginal bleeding, or vision disturbances. Seek immediate medical attention if these occur.

• Other: Hair loss, fluid retention, vaginal yeast infection, or depression. Consult a doctor if symptoms persist or worsen.

• Precautions: Contraindicated in patients with breast, uterine, or liver cancer, undiagnosed vaginal bleeding, blood clots, or liver disease. Use cautiously in patients with asthma, epilepsy, diabetes, kidney/heart conditions, or history of depression. Avoid smoking and excessive alcohol, as they increase blood clot risk. Inform your doctor of all medications to avoid interactions (e.g., with antifungals like ketoconazole, antiepileptics, or St. John’s Wort).